생화학분자생물학회입니다.
A novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development
작성자
Boksik Cha작성일자
2021-03-22조회수
445Name: Boksik, Cha ( boksik-cha@dgmif.re.kr ) | ||
2019-present | Senior Researcher, New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu City, Korea | |
2017-2019 | 2017-2019 Research Assistant Member, Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, OK, USA | |
20013-2017 | Postdoctoral research fellow, Cardiovascular Biology Research Program, Oklahoma Medical Research Foundation, OK, USA | |
2008-2013 | Ph.D., Department of Life Science, University of Seoul, Seoul, Korea |
A novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development
The lymphatic vasculature plays important roles in regulating fluid homeostasis, intestinal lipid absorption, and immune surveillance. Malfunction of lymphatic vasculature leads to several human diseases. Understanding the fundamental mechanism in lymphatic vascular development could provide a new therapeutic approach. Hippo-YAP/TAZ signaling pathway has emerged as a key player in controlling organ size and tissue homeostasis. Here, we review the molecular mechanisms by which Hippo-YAP/TAZ pathway regulating lymphatic specification, sprouting, and maturation.
https://pubmed.ncbi.nlm.nih.gov/33691907/
BMB Rep. 2021 Mar 11;5301. Online ahead of print.